Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p135 | (1) | WCRB2014

Interaction between galectin-1 and glycoconjugates is involved in hCG-mediated gene expression in cultured human luteinized granulosa cells

Nio-Kobayashi Junko , Iwanaga Toshihiko , Duncan W Colin

Introduction: The corpus luteum (CL) is a temporal endocrine organ secreting large amount of progesterone essential for the establishment and maintenance of pregnancy. The CL undergoes luteolysis in a non-fertile cycle, while the CL is rescued from luteolysis by human chorionic gonadotrophin (hCG) secreted from the conceptus during pregnancy. We recently revealed that a β-galactoside-binding lectin, galectin-1, plays important roles in the regulation of luteal rescue in t...